uhtbn

Psychedelic Drugs: Types, Uses, and Effects Balíková reports a fatal and nonfatal overdose after ingestion of the psychedelic phenethylamine 2,5-dimethoxy-4-bromoamphetamine by two male individuals. Gas chromatography–mass spectrometry was used to detect the presence of DOB in both gastric and urine samples of the two men. Although one subject survived, the other suffered convulsions and metabolic acidosis and died 6 days after admission. The most consistent finding for involvement of other receptors in the actions of psychedelics is the 5-HT1A receptor. That is particularly true for tryptamines and LSD, which generally have significant affinity and functional potency at this receptor. It is known that 5-HT1A receptors are colocalized with 5-HT2A receptors on cortical pyramidal cells (Martín-Ruiz et al., 2001), where the two receptor types have opposing functional effects . In addition to functioning as somatodendritic autoreceptors in the raphe, postsynaptic 5-HT1A receptors are al